Chimica Organica

AAC – AMINO ACIDS CHEMISTRY DEPARTMENT OF CHEMICAL SCIENCES AT UNINA Dr. Luigi Longobardo • Room 2N19; Lab 2N18ab; • phone +39-081-674115; • Email: luilongo@unina.it; luilongo@gmai.com • orcid • webdocenti • Group website: http://fco0809.blogspot.it/ Research: Asymmetric synthesis Synthetic manipulation of α-amino acids. Sulfur and selenium-containing unnatural amino acids. Chemistry of Hydroxycinnamic Acids.

15 giu 2026

Exploring the Antifungal, Antibiofilm, and Wound Healing In Vitro Properties of N-(4-Methoxycinnamoyl)-Anthranilic Acid as a Supportive Strategy for Ocular Fungal Infections

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  Open Access Article by Francesco Petrillo 1,† , Annalisa Buonanno 2,† , Angela Maione 2,* , Luigi Longobardo 3 , Michele Reibaldi 1 ,...
22 apr 2026

Sustainable Synthesis of Novel Hydroxylated Tranilast Analogues and Their Bioactivities

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  Molecules   2026 ,  31 (8), 1340;  https://doi.org/10.3390/molecules31081340 Abstract Tranilast, an anti-allergic drug with well-establish...
19 mar 2026

Eco-Friendly Synthesis of 2-Styryl-benzo[d][1,3]oxazin-4-ones from N-Cinnamoyl-Anthranilic Acids

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Molecules 2026 , 31 , 709 https://doi.org/10.3390/molecules31040709 Abstract: N-cinnamoyl anthranilic acids are synthesized in a single, eco...
14 lug 2025

Antifungal and Antibiofilm Activities of 2-Aminobenzoic Acid Derivatives Against a Clinical Ocular Candida albicans Isolate for Biomedical Applications

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Abstract :  Ocular fungal infections are slow-progressing conditions that primarily affect  the cornea but can also involve the entire eyeba...
29 apr 2025

Improved Chemical Synthesis of Avenanthramides Family and its Analogs by Mixed Anhydride Method

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Abstract Amides derived from common hydroxycinnamic acids — including 4-hydroxycinnamic acid, 3-methoxy-4-hydroxycinnamic acid, 3,4-dihydrox...

Sustainable Chemical Derivatization of Hydroxycinnamic Acids

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Graphical Abstract Hydroxycinnamic acids have been derivatized in ethyl acetate using N-methyl morpholine and an alkyl chloroformate to prot...

Research Activities

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6 mag 2020

Hydroxycinnamic amides and N-Hydroxycinnamoyl-amino acids

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doi.org/10.1002/slct.202000176 ...
5 mag 2020

Hydroxycinnamyl Alcohols

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A Facile Preparation of Hydroxycinnamyl Alcohols with Simultaneous Protection of Phenol Groups as C...
3 mar 2018

Novel thiol- and thioether-containing amino acids: cystathionine and homocysteine families

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Abstract  Natural L-homocysteine and L,L-cystathionine, along with a series of unnatural analogues, have been prepared from L-aspar...
2 mar 2018

A practical route to β2,3-amino acids with alkyl side chains

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Longobardo et al. SpringerPlus (2015) 4:553DOI 10.1186/s40064-015-1351-6 RESEARCH A practical route to β 2,3 -amino acids with alkyl ...
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